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Chemical abbreviations
This page houses a small list of chemical acronyms and abbreviations that are commonly used in peptide manufacturing chemistry.
| Abbreviation | Full Chemical Name |
|---|---|
| 1-Nal | β-(1-Naphthyl)-L-alanine |
| 2-Nal | β-(2-Naphthyl)-L-alanine |
| 4MbNA | 4-Methoxy-β-naphthylamide |
| Abu | L-α-Aminobutyric acid |
| Abz | 2-Aminobenzoyl (Anthraniloyl) |
| Ac | Acetyl |
| Acm | Acetamidomethyl |
| Ada | Adamantyl |
| AFC | 7-Amino-4-trifluoromethyl-coumaride |
| Aha | 7-Aminoheptanoic acid |
| Ahx | 6-Aminohexanoic acid (n-caproic acid) |
| Aib | α-Aminoisobutyric acid (α-Methyl-alanine) |
| Ala | Alanine |
| Aloc | Allyloxycarbonyl |
| AMC | 7-Amino-4-methyl-coumaride |
| Aph | Aminophenylalanine |
| Arg | Arginine |
| Asn | Asparagine |
| Asp | Aspartic Acid |
| Asu | L-α-Aminosuberic acid (L-2-Aminooctanoic acid) |
| Boc | t-Butoxycarbonyl |
| Bom | Benzyloxymethyl |
| BOP | Benzotriazole-1-yl-oxy-tris(dimethylamino)phosphoniumhexafluorophosphate |
| Bpa | 4-Benzoyl-L-phenylalanine |
| Bz | Benzoyl |
| Bzl | Benzyl |
| Cbz (Z) | Benzyloxycarbonyl |
| CDI | 1,1'-Carbonyldiimidazole |
| Cha | Cyclohexylalanine |
| Chg | L-Cyclohexylglycine |
| Cit | L-Citrulline |
| Cys | Cysteine |
| Dab | L-α,γ-Diaminobutyric acid |
| DABCYL | 4-(4-Dimethylaminophenylazo)benzoyl |
| Dap | Diaminopimelic acid |
| DCC | N,N'-Dicyclohexylcarbodiimide |
| DCHA | Dicyclohexylammonium salt |
| Dde | 1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl |
| DIC | 1,3-Diisopropylcarbodiimide |
| DIPEA | Diisopropylethylamine |
| DMAP | 4-Dimethylaminopyridine |
| DMF | N,N-Dimethylformamide |
| DMS | Dimethylsulfide |
| DMSO | Dimethylsulfoxide |
| Dnp | 2,4-Dinitrophenyl |
| Dpr | 2,3-Diaminopropionic acid |
| EDANS | 5-[(2-Aminoethyl)amino]naphthalene-1-sulfonyl |
| EDT | 1,2-Ethanedithiol |
| EEDQ | 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline |
| Et | Ethyl |
| FITC | Fluorescein isothiocyanate |
| Fm | Fluorenylmethyl |
| Fmoc | 9-Fluorenylmethyloxycarbonyl |
| For | Formyl |
| Gla | g-Carboxy-L-glutamic acid |
| Gln | Glutamine |
| Glp | Pyroglutamic Acid |
| Glu | Glutamic Acid |
| Gly | Glycine |
| HATU | O-(7-Azabenzotriazole-1-yl)-1,1,3,3-tetramethyluroniumhexafluorophosphate |
| HBTU | O-(Benzotriazole-1-yl)-1,1,3,3-tetramethyluroniumhexafluorophosphate |
| His | Histidine |
| HOAt | 1-Hydroxy-7-azabenzotriazole |
| HOBt | 1-Hydroxybenzotriazole |
| Homoarg | L-Homoarginine (L-α-Amino-ε-guanidinohexanoic acid) |
| Homocit | L-Homocitrulline (L-α-Amino-ε-ureidohexanoic acid) |
| Hse | Homoserine |
| Hyp | trans-4-Hydroxy-L-proline |
| Ile | Isoleucine |
| iPr | iso-Propyl |
| Leu | Leucine |
| Lys | Lysine |
| MBHA | 4-Methylbenzhydrylamine |
| Mbs | 4-Methoxybenzenesulfonyl |
| Mbzl | 4-Methylbenzyl |
| Mca | (7-Methoxycoumarin-4-yl)acetyl |
| Me | Methyl |
| MeOSuc | Methoxysuccinyl |
| Met | Methionine |
| Met(O) | L-Methionine sulfoxide |
| Met(O)2 | L-Methionine sulfone |
| Mmt | 4-Methoxytrityl |
| Mob | 4-Methoxybenzyl |
| Mpr | 3-Mercaptopropionyl |
| Mtt | 4-Methyltrityl |
| Nal | Naphthylalanine |
| NHEt | Ethylamide |
| NHMe | N-Methylamide |
| NHNH2 | Hydrazide |
| NHOH | Hydroxamate |
| Nic | Nicotinyl |
| Nle | Norleucine |
| NMe2 | N,N-Dimethylamide |
| NMP | N-Methylpyrrolidine |
| NO2 | Nitro |
| Nps | 2-Nitrophenylsulfenyl |
| NPys | 3-Nitro-2-pyridinesulfenyl |
| OBzl | Benzyl ester |
| OcHex | Cyclohexyl ester |
| OEt | Ethyl ester |
| OFm | Fluorenylmethyl ester |
| OHex | Hexyl ester |
| Oic | L-Octahydroindole-2-carboxylic acid |
| OMe | Methyl ester |
| ONp | p-Nitrophenyl ester |
| OPcp | Pentachlorophenyl ester |
| OPfp | Pentafluorophenyl ester |
| OPh | Phenyl ester |
| Orn | Ornithine |
| OSu | Succinimide ester |
| OtBu | t-Butyl ester |
| Pal | 2-Pyridylalanine |
| Pbf | 2,2,4,6,7-Pentamethyldihydrobenzofuran-5-sulfonyl |
| PEG | Polyethylene glycol |
| Pen | L-Penicillamine (β,β-Dimethyl-L-cysteine) |
| Phaa | Phenylacetic acid |
| Phe | Phenylalanine |
| Phg | L-Phenylglycine |
| Pmp | β-Mercapto-β,β-cyclopentamethylene propionic acid |
| pNA | p-Nitroanilide |
| Pro | Proline |
| pSer | Phospho-L-serine |
| pThr | Phospho-L-threonine |
| pTyr | Phospho-L-tyrosine |
| Pyr | (pGlu) L-Pyroglutamic acid |
| Sar | Sarcosine (N-Methylglycine) |
| Ser | Serine |
| Sta | Statyl- ((3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl) |
| Suc | Succinyl |
| TBTU | O-Benzotriazole-1-yl-1,1,3,3-tetramethyluroniumtetrafluoroborate |
| tBu | t-Butyl |
| TEA | Triethylamine |
| TFA | Trifluoroacetic acid |
| Tfa | Trifluoroacetyl |
| TFE | 2,2,2-Trifluoroethanol |
| Thr | Threonine |
| Tic | L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid |
| Tos | Tosyl (4-Toluenesulfonyl) |
| Trp | Tryptophan |
| Trt | Trityl |
| Tyr | Tyrosine |
| Tyr(Me) | Methyltyrosine |
| Val | Valine |
| Xan | Xanthyl |
| Z (Cbz) | Benzyloxycarbonyl |
| β-Ala | β-Alanine |
| βNA | β-Naphthylamide |
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